KPV is a short peptide that has attracted attention in recent years for its potential therapeutic applications, particularly in the field of inflammation and immune modulation. Because it is a small molecule composed of only three amino acids—lysine, proline, and valine—it can be synthesized relatively easily and at a lower cost than larger biologics, making it an attractive candidate for researchers and clinicians seeking novel anti-inflammatory strategies.
What is KPV?
KPV stands for the tripeptide sequence Lys-Pro-Val. It was first identified in the context of gastrointestinal research where it showed potent anti-inflammatory effects on gastric mucosa. Since then, studies have expanded to examine its role in other tissues and systems. The peptide functions by interacting with specific receptors on immune cells, thereby dampening inflammatory signaling pathways such as NF-κB activation and reducing the production of pro-inflammatory cytokines like tumor necrosis factor alpha and interleukin-6. In animal models, KPV has demonstrated protective effects against ulcerative colitis, arthritis, and even certain types of dermatitis, suggesting a broad spectrum of action.
KPV 10mg
When discussing dosage, it is common to see references to a 10 milligram formulation of the peptide. This concentration typically refers to the amount contained in a single vial or capsule, which can be used for intravenous infusion or oral administration depending on the intended therapeutic route. For researchers working in preclinical settings, a 10 mg dose allows for convenient scaling when testing multiple animals or cell cultures. In clinical scenarios, the dosage would need to be adjusted based on patient weight, severity of disease, and pharmacokinetic data derived from early phase trials.
Products
Several manufacturers now offer KPV peptides suitable for research use. These products vary in purity levels, excipient composition, and packaging options. A common format is a lyophilized powder that can be reconstituted with sterile water or buffer solutions to achieve the desired concentration. Some vendors provide pre-filled syringes ready for injection, which are especially useful for studies requiring precise dosing without additional preparation steps.
The typical product specifications include:
Purity: 95 % or higher, as verified by high-performance liquid chromatography and mass spectrometry.
Stability: Stable at room temperature for up to six months; refrigerated storage extends shelf life beyond one year.
Sterility: Manufactured under GMP conditions with endotoxin levels below acceptable thresholds for in vitro and in vivo work.
For those looking to purchase KPV 10 mg, it is advisable to compare product catalogues from reputable suppliers. Key factors include batch consistency, availability of supporting documentation such as certificates of analysis, and the vendor’s track record for customer support. Additionally, some companies offer custom synthesis options where researchers can specify modifications like PEGylation or labeling with fluorescent tags to facilitate imaging studies.
In summary, KPV is a promising anti-inflammatory tripeptide that has been studied across various disease models. Its 10 mg formulations are commonly used in research settings for both in vitro assays and animal experiments. When selecting a product, researchers should focus on purity, stability, and supplier reliability to ensure reproducible and meaningful results.
